Search on: OROTIDINE-5'-PHOSPHATE PYROPHOSPHORYLASE 
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Descriptor English:   Orotate Phosphoribosyltransferase 
Descriptor Spanish:   Orotato Fosforribosiltransferasa 
Descriptor Portuguese:   Orotato Fosforribosiltransferase 
Synonyms English:   Orotidine-5'-Phosphate Pyrophosphorylase
Orotidylic Acid Phosphorylase  
Tree Number:   D08.811.913.400.725.700
Definition English:   The enzyme catalyzing the formation of orotidine-5'-phosphoric acid (orotidylic acid) from orotic acid and 5-phosphoribosyl-1-pyrophosphate in the course of pyrimidine nucleotide biosynthesis. EC 2.4.2.10. 
Indexing Annotation English:   /defic: consider also OROTIC ACID /urine (IM) + PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS (IM)
History Note English:   91(77); was see under PENTOSYLTRANSFERASES 1977-90 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   10140 
Unique Identifier:   D009962 

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